Biotechnology is the “integration of physical science and engineering to enable the application of molecular analogs to living organisms, cells, parts thereof, and products and services.” The term biotechnology, first used by KAROLY EREKY in 1919, refers to the production of goods from raw materials with the help of living organisms                                                                The term biotechnology is broadly derived from the domestication of animals, the cultivation of plants, and their “improvement” by breeding programs that employ artificial selection and includes genetic engineering and cell and tissue culture techniques. the American chemistry society defines biotechnology as the application of organisms, system or processes by various industries to learn about the science of life and increase the value about of materials and organisms such as medicines, plants, and livestock. According to the European Federation of biotechnology, biotechnology is the integration of science and biology , cells, parts of them, and molecular analogs into products and services. biotechnology is built on basic biology(molecular biology, biochemistry, cell biology, embryology, genetics, microbiology) and supports basic biology research. and provide a way to do it.                                       Biotechnology can use bioinformatics to design high value-added products (Eg, reproducible by biosynthesis) for bioengineered discovery, extraction, utilization, and biomass source. development. sustainable operation(in return for a bottomless initial investment in research and development) and permanent patent acquisition (for exclusive marketing rights, and for animal testing and human testing, especially undetected side effects when using the product) Biotechnology's pharmaceutical sector to avoid safety concerns. Biotechnology's is the use of biological processes, organisms, or systems to improve people's lives. is to produce the expected product.                                                                                                          In contrast, biotechnology is generally regarded as a relevant discipline that relies heavily on biological connections and more sophisticated systemic approaches to biological utilization(not necessarily direct modification or use of biological materials) Biotechnology is the application of engineering and scientific principles to tissues, cell and molecules. the can be seen as achieving results that can enhance the function of plants and animals using the knowledge gained from manipulating and manipulating biology. Therefore, biomedical engineering can be applied utilizing biotechnology (by various definitions), especially in specific subfields of biomedical or chemical engineering such as tissue engineering, biopharmaceutical engineering genetic engineering. there are many overlapping fields.                                             Agriculture has been considered the dominant mode of food production since the NEOLITHIC Revolution. through early biotechnology, the most suitable corps with the highest yields in order to produce enough food to support the growing population.